Oxidant-antioxidant status of erythrocytes in chronic obstructive pulmonary disease

Abstract

In 70 patients with COPD studied mechanisms of oxidative stress on the changes in oxidant-antioxidant status of erythrocytes. Found that the intensity of oxidative stress in red blood cells is directly dependent on the severity of the disease. Maximum activity of antioxidant enzymes found in patients with secondary erythrocytosis with stage II disease. In patients with stage III COPD, oxidative stress was significantly expressed and is associated with a sharp fall in activity of antioxidant systems.

Keywords

• ХОБЛ
• окислительный стресс
• эритроциты
• антиоксидантные системы
• вторичный эритроцитоз