Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films

Dilshad Qureshi; Ayasharani Sahoo; Biswaranjan Mohanty; Arfat Anis; Viktoryia Kulikouskaya; Kseniya Hileuskaya; Vladimir Agabekov; Preetam Sarkar; Sirsendu Sekhar Ray; Samarendra Maji; Kunal Pal

doi:10.3390/gels7020055

Gels (May 2021)

Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films

Dilshad Qureshi,
Ayasharani Sahoo,
Biswaranjan Mohanty,
Arfat Anis,
Viktoryia Kulikouskaya,
Kseniya Hileuskaya,
Vladimir Agabekov,
Preetam Sarkar,
Sirsendu Sekhar Ray,
Samarendra Maji,
Kunal Pal

Affiliations

Dilshad Qureshi: Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, India
Ayasharani Sahoo: Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, India
Biswaranjan Mohanty: Institute of Pharmacy and Technology, Salipur 754202, India
Arfat Anis: SABIC Polymer Research Center, Department of Chemical Engineering, King Saud University, Riyadh 11451, Saudi Arabia
Viktoryia Kulikouskaya: The Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, 220141 Minsk, Belarus
Kseniya Hileuskaya: The Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, 220141 Minsk, Belarus
Vladimir Agabekov: The Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, 220141 Minsk, Belarus
Preetam Sarkar: Department of Food Process Engineering, National Institute of Technology, Rourkela 769008, India
Sirsendu Sekhar Ray: Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, India
Samarendra Maji: Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India
Kunal Pal: Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, India

DOI: https://doi.org/10.3390/gels7020055
Journal volume & issue: Vol. 7, no. 2
p. 55

Abstract

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In the present study, we report the development of poly (vinyl alcohol) (PVA) and chitosan oligosaccharide (COS)-based novel blend films. The concentration of COS was varied between 2.5–10.0 wt% within the films. The inclusion of COS added a brown hue to the films. FTIR spectroscopy revealed that the extent of intermolecular hydrogen bonding was most prominent in the film that contained 5.0 wt% of COS. The diffractograms showed that COS altered the degree of crystallinity of the films in a composition-dependent manner. As evident from the thermal analysis, COS content profoundly impacted the evaporation of water molecules from the composite films. Stress relaxation studies demonstrated that the blend films exhibited more mechanical stability as compared to the control film. The impedance profiles indicated the capacitive-dominant behavior of the prepared films. Ciprofloxacin HCl-loaded films showed excellent antimicrobial activity against Escherichia coli and Bacillus cereus. The prepared films were observed to be biocompatible. Hence, the prepared PVA/COS-based blend films may be explored for drug delivery applications.

Published in Gels

ISSN: 2310-2861 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry; Science: Chemistry: General. Including alchemy
Website: http://www.mdpi.com/journal/gels

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