Atrazine-Induced Hepato-Renal Toxicity in Adult Male <i>Xenopus laevis</i> Frogs

Abstract

Atrazine (ATZ) is an herbicide commonly detected in groundwater. Several studies have focused on its immunological and endocrine effects on adult Xenopus laevis species. However, we investigated the impact of atrazine on the renal and hepatic biochemistry and histomorphology in adult male frogs. Forty adult male frogs were allocated to four treatment groups (control, one ATZ (0.01 µg/L), two ATZ (200 µg/L) and three ATZ (500 µg/L), 10 animals per group, for 90 days. Alanine aminotransferase (ALT) and creatinine levels increased significantly (p p Xenopus laevis frogs and potentially related aquatic organisms.

Keywords

• atrazine
• hepatorenal
• pathology
• toxicosis
• biomarkers
• adult <i>Xenopus laevis</i>