Sequence-Selective Recognition of the d(GGCGCC)2 DNA Palindrome by Oligopeptide Derivatives of Mitoxantrone. Enabling for Simultaneous Targeting of the Two Guanine Bases Upstream from the Central Intercalation Site in Both Grooves and along Both Strands

• Nohad Gresh,
• Alberto Ongaro,
• Luc Demange,
• Giuseppe Zagotto,
• Giovanni Ribaudo

Affiliations

Nohad Gresh

Laboratoire de Chimie Théorique, UMR 7616 CNRS Sorbonne Universités, Paris, France

Alberto Ongaro

Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy

Luc Demange

UMR 8038 CNRS CiTCoM, Team PNAS, Faculté de Pharmacie, Université Paris-Cité, Paris, France

Giuseppe Zagotto

Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy

Giovanni Ribaudo

DMMT, University of Brescia, Brescia, Italy