Healing effects of Arnebia euchroma on burn wound in rats: a systematic review

Abstract

Background & Aims: Nowadays, herbal medicine with antimicrobial and anti-inflammatory activities, such as Arnebia euchroma, has been considered in the treatment of burn wounds. Therefore, this study aimed to determine the healing effect of Arnebia euchroma L on burn wounds in rats by reviewing the results of published studies in this field. Materials & Methods: The keywords "Arnebia euchroma", "burn", and "rat", and their synonyms were explored in PubMed, Scopus, and ScienceDirect for English articles, and SID, Magiran, and Irandoc for Persian articles without time limitation until May 4, 2021. Inclusion criteria for this study were laboratory research articles focused on the effect of Arnebia euchroma L on wound healing in rats. Finally, the included studies were reviewed and assessed according to the given criteria. Results: Amongst the seven articles included in this research, four articles studied the healing effect of the medicine on second-degree burn wounds, one article addressed third-degree burn wounds, and two articles generally studied burn wounds. Arnebia euchroma L has been found to be effective in healing burn wounds in approximately 57% of studies, while the rest of the studies have emphasized its ineffectiveness in accelerating burn wound healing. Conclusion: The literature review demonstrated that Arnebia euchroma is effective in both healing and accelerating the recovery of burn wounds. Since there is an insignificant difference between the number of studies that have found this medicine effective and the number of those that have found it ineffective, further studies are required to determine the effectiveness of this medicine.

Keywords

• arnebia euchroma
• burn
• systematic review
• wound