Laryngoscope Investigative Otolaryngology (Aug 2024)

Current otolaryngologic applications of the novel self‐assembling RADA‐16 peptide matrix

  • Kaitlynne Y. Pak,
  • Dennis M. Tang,
  • Satyan B. Sreenath,
  • Christopher J. Ito,
  • Brent A. Senior,
  • Kent K. Lam,
  • Thomas S. Higgins,
  • Kevin Hur,
  • Benjamin Tam,
  • Ayesha N. Khalid,
  • Arthur W. Wu

DOI
https://doi.org/10.1002/lio2.1299
Journal volume & issue
Vol. 9, no. 4
pp. n/a – n/a

Abstract

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A novel bioresorbable agent on the market is PuraGel® (3‐D Matrix, Tokyo, Japan), a RADA‐16 product that acts as a synthetic hemostatic and space‐filling gel that promotes wound healing and prevents adhesion formation. Given the reported benefits of accelerated wound healing and scar tissue prevention, there are multiple otolaryngologic applications where RADA‐16 might improve outcomes. Our study highlights current utilization and associated post‐operative complications with this product.

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