Current Issues in Molecular Biology (Jun 2022)

Insights into the Uses of Traditional Plants for Diabetes Nephropathy: A Review

  • Haleema Shahin D. H.,
  • Rokeya Sultana,
  • Juveriya Farooq,
  • Tahreen Taj,
  • Umaima Farheen Khaiser,
  • Nader Sulaiman Ayyt Alanazi,
  • Mohammed Kanan Alshammari,
  • Mohammad Nazal Alshammari,
  • Firas Hamdan Alsubaie,
  • Syed Mohammed Basheeruddin Asdaq,
  • Abdulmueen A. Alotaibi,
  • Abdulrhman ahmed Alamir,
  • Mohd. Imran,
  • Shahamah Jomah

DOI
https://doi.org/10.3390/cimb44070199
Journal volume & issue
Vol. 44, no. 7
pp. 2887 – 2902

Abstract

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Diabetic nephropathy (DN) is a serious kidney illness characterized by proteinuria, glomerular enlargement, reduced glomerular filtration, and renal fibrosis. DN is the most common cause of end-stage kidney disease, accounting for nearly one-third of all cases of diabetes worldwide. Hyperglycemia is a major factor in the onset and progression of diabetic nephropathy. Many contemporary medicines are derived from plants since they have therapeutic properties and are relatively free of adverse effects. Glycosides, alkaloids, terpenoids, and flavonoids are among the few chemical compounds found in plants that are utilized to treat diabetic nephropathy. The purpose of this review was to consolidate information on the clinical and pharmacological evidence supporting the use of a variety of medicinal plants to treat diabetic nephropathy.

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