PLoS ONE (Jan 2023)

Association between zinc deficiency and aorta stiffness in non-diabetic hemodialysis patients.

  • Kunihiro Ishioka,
  • Sumi Hidaka,
  • Naoki Fujiwara,
  • Mizuki Yamano,
  • Yasuhiro Mochida,
  • Machiko Oka,
  • Kyoko Maesato,
  • Hidekazu Moriya,
  • Takayasu Ohtake,
  • Shuzo Kobayashi

DOI
https://doi.org/10.1371/journal.pone.0268875
Journal volume & issue
Vol. 18, no. 1
p. e0268875

Abstract

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ObjectivesZinc deficiency (Zn MethodsOf 150 patients receiving maintenance HD at our hospital, we included 79 non-diabetic HD patients (age: 70±11 years, 49 men) after excluding 71 diabetic HD patients. Zinc deficiency was defined as Zn ResultsThe zinc deficiency group (ZD group) included 45 patients (57.0%). Compared to the zinc non-deficiency group (ZND group), patients with ZD group were significantly older, higher levels of CRP and hypoalbuminemia. Moreover, they had significantly higher levels of baPWV, and lower levels of ankle-brachial pressure index (ABI) (pConclusionThe study suggested that zinc deficiency may be an independent risk factor for aorta stiffness, even after adjusting for malnutrition and inflammation.