Raman spectroscopy diagnosis of skin tumor

Abstract

A method for type diagnosis of skin cancers was developed based on the localization changes in the spectral intensity of Raman bands in the 13001340 cm^-1 and 16401680 cm^-1 in relation to the intensity of the 1450 cm^-1 in the phase plane. It was shown, based on ex vivo experiments carried out on 28 samples of skin tumors, that the sensitivity of the proposed method is close to absolute value, and the specificity over 90 %. Phase method can be used for the diagnosis of melanoma and basal cell carcinoma in mass screening and monitoring of skin pathologies.

Keywords

• raman spectroscopy
• skin tumors
• oncology
• histology
• phase method