Micronucleus level in exfoliated buccal mucosa cells of cancer patients

Abstract

Micronucleus levels in exfoliated buccal mucosa cells of patients with primary breast, lung, cervix uteri cancer, and patients with Hodgkin's disease were studied (n=59). Significantly increased number of micronuclei in cells of cancer patients was observed compared with healthy persons (n=45). The evaluation of micronuclei number in buccal mucosa cells shows genomic instability in somatic cells of humans.

Keywords

• Micronucleus tests
• mouth mucosa
• neoplasms