Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas

Huawei Zhang; Menglian Dong; Jianwei Chen; Hong Wang; Karen Tenney; Phillip Crews

doi:10.3390/md15110351

Marine Drugs (Nov 2017)

Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas

Huawei Zhang,
Menglian Dong,
Jianwei Chen,
Hong Wang,
Karen Tenney,
Phillip Crews

Affiliations

Huawei Zhang: Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Menglian Dong: Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Jianwei Chen: Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Hong Wang: Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Karen Tenney: Department of Chemistry & Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, USA
Phillip Crews: Department of Chemistry & Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, USA

DOI: https://doi.org/10.3390/md15110351
Journal volume & issue: Vol. 15, no. 11
p. 351

Abstract

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The marine sponge genus Agelas comprises a rich reservoir of species and natural products with diverse chemical structures and biological properties with potential application in new drug development. This review for the first time summarized secondary metabolites from Agelas sponges discovered in the past 47 years together with their bioactive effects.

Published in Marine Drugs

ISSN: 1660-3397 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/marinedrugs

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