Scientific Reports (Nov 2024)

Stereo slit-scanning tomography of the anterior segment of the human eye

  • Alfonso Jiménez-Villar,
  • Alexander Matteson,
  • David Huang,
  • Travis K. Redd,
  • Donna Kim,
  • Siyu Chen

DOI
https://doi.org/10.1038/s41598-024-78101-2
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

Read online

Abstract We demonstrate a new tomographic imaging device for 2D cross-sectional and 3D volumetric images of the anterior eye segment. The optical system combines optical sectioning with a stereoscopic camera setup to determine the true spatial location of the ocular structures. Moreover, we propose a calibration procedure to estimate the triangulation function that links the stereo camera pixel indices with the eye-referenced 3D spatial coordinates. The proposed instrument will image the entire anterior chamber and contiguous structures, including the corneal limbus, sclera and eyelids. Furthermore, the system can obtain corneal topography. Finally, we studied the repeatability of the instrument and its agreement with a commercial Scheimpflug imaging tomographer in a group of healthy subjects.