Proliferative Activity (Ki-67 Expression) and Outcome in High Grade
Osteosarcoma: A Study of 27 Cases

Roland  Jong; Aileen M. Davis; Maria G. Mendes; Jay S. Wunder; Robert S. Bell; Rita  Kandel

doi:10.1155/S1357714X00000086

Sarcoma (Jan 2000)

Proliferative Activity (Ki-67 Expression) and Outcome in High Grade Osteosarcoma: A Study of 27 Cases

Roland Jong,
Aileen M. Davis,
Maria G. Mendes,
Jay S. Wunder,
Robert S. Bell,
Rita Kandel

Affiliations

Roland Jong: Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Aileen M. Davis: University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Maria G. Mendes: Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Jay S. Wunder: University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Robert S. Bell: University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Rita Kandel: Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada

DOI: https://doi.org/10.1155/S1357714X00000086
Journal volume & issue: Vol. 4, no. 1-2
pp. 47 – 55

Abstract

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Purpose. Although pre-operative chemotherapy has improved the prognosis for individuals with osteosarcoma, approximately 40% of patients will die of their disease.The aim of this study was to quantitate proliferative activity in high grade osteosarcomas and to determine whether proliferation is a prognostic factor.

Published in Sarcoma

ISSN: 1357-714X (Print); 1369-1643 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://onlinelibrary.wiley.com/journal/5805

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