Taiwanese Journal of Obstetrics & Gynecology (Jun 2018)

Chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin improved spontaneous pneumothorax and thoracic endometriosis: The first case involving a pregnant woman

  • Ippei Yasuda,
  • Takao Hidaka,
  • Tae Kusabiraki,
  • Keiko Kochi,
  • Kuniaki Yasoshima,
  • Kiyoshi Takagawa,
  • Shigeru Saito

DOI
https://doi.org/10.1016/j.tjog.2018.04.022
Journal volume & issue
Vol. 57, no. 3
pp. 449 – 451

Abstract

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Objective: Spontaneous pneumothorax combined with thoracic endometriosis is a rare condition during pregnancy. We present a case of chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin during pregnancy. Case report: This report presents a case of spontaneous pneumothorax combined with thoracic endometriosis that arose at 22 weeks' gestation in a 35-year-old female. The initial chest drainage was unsuccessful. At 25 weeks' gestation, video-assisted thoracoscopic surgery was performed and revealed endometriosis in the thoracic cavity. Since the leak persisted, chemical pleurodesis was performed with autologous blood and freeze-dried concentrated human thrombin at 28 weeks’ gestation. The leak improved markedly and did not recur. Conclusion: This is the first case report about chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin during pregnancy. This procedure might contribute to the management of pneumothorax in pregnant women.

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