The Crohn’s disease-related bacterial strain LF82 assembles biofilm-like communities to protect itself from phagolysosomal attack

Abstract

Prudent et al. show that intracellular bacteria related to the Crohn’s disease, LF82, produce an extra-bacterial matrix that acts as a biofilm and controls the formation of LF82 intracellular bacterial communities. This study provides insights into the strategies that adherent invasive E. coli use to establish their replicative niche within macrophages.