Features of studying angiogenesis factors in patients with arterial hypertension and associated clinical conditions

Abstract

The study of angiogenesis factors in patients with cardiovascular disease by determining the plasma concentration of endostatin and vascular growth factor (VEGF). 82 patients with cardiovascular disease (CVD) and 19 healthy volunteers were examined. Revealed that the level of endostatin is reliably higher among patients with high blood pressure (BP) than in relatively healthy persons. Established that the maximum values of VEGF were in patients with arterial hypertension (AH) and acute coronary syndrome (ACS) in history. The VEGF level was reliably lower in patients with hypertension only persons. Maximum values of endostatin were observed in patients who had undergone ACS.

Keywords

• артериальная гипертензия
• эндостатин
• эндотелиальный фактор роста
• hypertension
• endostatin
• vascular endothelial growth factor