Diabetes mellitus: the role of genetic factors in the onset of the disease

Abstract

This paper presents the analysis of the data of studies on the genetics of type 2 diabetes mellitus. High scientific quality papers of the recent years were used to prepare this work. The article deals with the role of single-nucleotide polymorphisms in genes associated with the development of diabetes mellitus, prognosis of the disease and efficacy of the treatment. It also discusses the role of environmental factors in the development of diabetes mellitus and the use of results of genetics trials in practice.

Keywords

• type 2 diabetes mellitus
• genetics
• insulin resistance
• beta-cell dysfunction