Fasciola hepatica isolates induce different immune responses in unmaturated bovine macrophages

Abstract

Introduction:Fasciola hepatica (liver fluke) is a parasite of great socioeconomic importance. A number of fluke isolates have been identified; however, to date the differences between the immunomodulatory properties of different parasite isolates have not been sufficiently investigated. The aim of this study was to explore differences between the immunomodulatory properties of two F. hepatica isolates using unmaturated bovine macrophages.

Keywords

• fasciola hepatica
• macrophages
• gene expression
• immunoregulation
• immune modulation