Synthesis of spiro 1,3-oxazolidines via palladium-catalyzed [3 + 2] cycloaddition of vinyl epoxides with cyclohexadienimines

Abstract

A palladium-catalyzed chemoselective [3 + 2] cycloaddition of vinyl epoxide with cyclohexadienimines was developed. The reaction gave rise to a range of spiro 1,3-oxazolidines in moderate to good yields.

Keywords

• Spiro 1,3-oxazolidine
• Palladium-catalyzed
• Cycloaddition