Медицинский совет (Dec 2015)

Bacteriophages in the treatment of acute intestinal infections

  • N. V. Topchiy,
  • A. S. Toporkov

DOI
https://doi.org/10.21518/2079-701X-2015-8-74-81
Journal volume & issue
Vol. 0, no. 8
pp. 74 – 81

Abstract

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Management of acute intestinal infections remains relevant because of their high incidence, clinical aggravation of certain forms of infection, development of resistance of pathogens to traditional etiotropic medications, and an increase in side effects of antibiotic therapy. Excessive use of antibiotic therapy, even in less severe infections, as well as inadequate use of chemotherapy, may contribute to the development of dysbacteriosis manifested in antibiotic-associated diarrhea. In this case, bacteriophages could be an alternative to antibiotics in the treatment of bacterial diarrhea. Both infectionists and general practitioners should be prepared to develop a set of actions for the prevention and treatment of acute intestinal infections through bacteriophages and step-by-step diet therapy.

Keywords