Sociodemographic and Lifestyle Risk Factors Associated with Fragility Hip Fractures: A Systematic Review and Meta-Analysis

Diana Yeritsyan; Kaveh Momenzadeh; Amin Mohamadi; Sharri J. Mortensen; Indeevar R. Beeram; Daniela Caro; Nadim Kheir; Megan McNichol; John J. Wixted; Paul Appleton; Arvind von Keudell; Ara Nazarian

doi:10.3390/osteology4020006

Osteology (May 2024)

Sociodemographic and Lifestyle Risk Factors Associated with Fragility Hip Fractures: A Systematic Review and Meta-Analysis

Diana Yeritsyan,
Kaveh Momenzadeh,
Amin Mohamadi,
Sharri J. Mortensen,
Indeevar R. Beeram,
Daniela Caro,
Nadim Kheir,
Megan McNichol,
John J. Wixted,
Paul Appleton,
Arvind von Keudell,
Ara Nazarian

Affiliations

Diana Yeritsyan: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Kaveh Momenzadeh: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Amin Mohamadi: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Sharri J. Mortensen: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Indeevar R. Beeram: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Daniela Caro: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Nadim Kheir: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Megan McNichol: Knowledge Services, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
John J. Wixted: Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Paul Appleton: Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Arvind von Keudell: Harvard Orthopaedic Trauma Initiative, Harvard Medical School, Boston, MA 02215, USA
Ara Nazarian: Musculoskeletal Translational Innovation Initiative, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

DOI: https://doi.org/10.3390/osteology4020006
Journal volume & issue: Vol. 4, no. 2
pp. 64 – 87

Abstract

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Hip fractures inflict heightened morbidity and mortality upon older adults. Although previous studies have explored the impact of individual demographic factors on hip fracture risk, a comprehensive review can help reconcile disparities among these factors. This meta-analysis encompassed 69 studies involving 976,677 participants and 99,298 cases of hip fractures. We found that age ≥ 85 (OR = 1.75), BMI 30 (OR = 0.38), parity (OR = 0.79), non-Caucasian descent (overall OR = 0.4, Asian OR 0.36, Black OR = 0.39, and Hispanic OR = 0.45), and rural residence (OR = 0.95) were significantly associated with a diminished risk of hip fracture. Hip fracture patients exhibited significantly lower weight and BMI than the non-fracture group, while their age was significantly higher. However, age at menopause and height did not significantly differ between the two groups.

Published in Osteology

ISSN: 2673-4036 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Other systems of medicine: Osteopathy
Website: https://www.mdpi.com/journal/osteology

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