Memorias do Instituto Oswaldo Cruz (May 2011)

First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil

  • Deuseli Quaresma de Figueiredo,
  • Kátia Regina Netto dos Santos,
  • Eliezer Menezes Pereira,
  • Ricardo Pinto Schuenck,
  • Cláudia Rezende Vieira de Mendonça-Souza,
  • Lúcia Martins Teixeira,
  • Silvia Susana Bona de Mondino

DOI
https://doi.org/10.1590/S0074-02762011000300019
Journal volume & issue
Vol. 106, no. 3
pp. 368 – 370

Abstract

Read online

Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the blaOXA-23-like, blaOXA-24-like, blaOXA-58-like and blaOXA-51-like genes. The blaOXA-58 and blaOXA-23 genes were detected in one and three isolates, respectively. Sequencing of the blaOXA-58-like amplicon revealed 100% identity with the A. baumannii blaOXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil.

Keywords