The comparisons of clinical efficacy of steroidal and nonsteroidal anti inflammatory drugs in the treatment of canine food allergies

Abstract

The purpose of this study was to compare the clinical efficacy of steroidal and nonsteroidal antiinflammatory drugs in dogs suffered from food allergy. Totally 24 dogs having food allergy were used in the study. Eleven of which were served steroid group and remaining 13 dogs assigned to nonsteroid group. Al dogs were examined physically and the age, breed and sex of the dogs and the skin lesions (pruritis, alopecia, erythema. hyper-pigmentation. papules. pustules. crusts. saborhea. acute moist dermatitis, folliculitis and pyoderma) and their severity and localisation were recorded before the treatment in all dogs. The blood samples were taken and serum biochemistry profile were interpreted before and after treatment Autohaemotherapy was applied in all dogs While Ery tromycine (5 mg/kg body weight). dexamethasone (0.5-1 mg body weight) and tripelennamine (1 cc/20 kg body weight) therapy was applied to the steroid group of dogs. in the dogs of nonsteroid group erytromycine (5 mg/kg body weight) and fluniksin meglumine (0.3 mg/kg body weight) were given. This treatment was ceased when the skin lesions were resolved completely The resolution of skin lesions were started at 3th days and pruritis was decreased in the nonsteroid group while starting therapy response was 5th days in the steroid group. Therapy course was lasted 7 and 5 days in 6 and 5 dogs respectively. Hovewer therapy course was lasted 5 days in all dogs of nonsteroid group. In conclusion. flunixin meglumine was found to be more effective drug the both clinical efficacy and therapy course compared with deksamethasone in the medical treatment of food allergy.

Keywords

• food allergy
• flunixin
• dexamethasone
• dog