Anti-Allergic Effect of Low Molecular Weight Digest from Abalone Viscera on Atopic Dermatitis-Induced NC/Nga

Abstract

Abalone viscera (AV) is one of the byproducts of the seafood processing industry. The low molecular weight (Dermatophagoides farinae. The results demonstrated that the LMW-AV reduced a number of clinical symptoms, such as the severity of the dermatitis and serum immunoglobulin E levels. Moreover, LMW-AV could inhibit the expression of chemokines and cytokines. The histological analysis indicated that the LMW-AV has suppressed the eosinophil count and the mast cell infiltration into the upper dermis. The results suggest that LMW-AV can be considered as a promising candidate for AD treatment.

Keywords

• atopic dermatitis
• abalone viscera
• <i>Haliotis discus hannai</i>
• gastrointestinal digest
• <i>Dermatophagoides farina</i>