Nature Communications (Oct 2016)

Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala

  • Kenneth M. McCullough,
  • Dennis Choi,
  • Jidong Guo,
  • Kelsey Zimmerman,
  • Jordan Walton,
  • Donald G. Rainnie,
  • Kerry J. Ressler

DOI
https://doi.org/10.1038/ncomms13149
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 13

Abstract

Read online

Activation of Thy-1 expressing neurons in the basolateral amygdala (BLA) has been shown to result in inhibition of fear. Here the authors present a comprehensive workflow to identify genes that are upregulated in this population and can be pharmacologically targeted to enable fear extinction.