脑血管病全血样本的采集、储存及转运标准化流程与解决方案 A Standardized Scheme of Collection, Storage and Transportation of Whole Blood Samples of Cerebrovascular Disease

Abstract

随着精准医学和大数据时代来临，构建标准化临床样本库成为脑血管病基础和转化研究的重要前提。脑血管病全血样本不稳定、批次效应强、难转运，其标准化采集、保存和运输全血样本成为构建脑血管病临床样本库的关键问题。首都医科大学附属北京天坛医院脑血管病生物样本库基于国际标准化组织的方案，形成了我国脑血管病全血样本采集、保存、运输全过程标准框架。该解决方案实现了全血样本标准、规范、及时、可靠的收集与管理，可为脑血管病临床诊疗、疾病研究、药物开发等方向提供技术保障。 Abstract: With the advent of the era of precision medicine and big data, the construction of a standardized clinical sample database has become an important prerequisite for the basic and transformational research of cerebrovascular diseases. Cerebrovascular disease whole blood samples are unstable, batch effect is strong, difficult to transport, so how to standardize the collection, preservation and transportation of whole blood samples has become a key issue in the construction of cerebrovascular disease clinical sample database. Based on the scheme of International Standardization Organization, the center for biological sample database of cerebrovascular diseases in Beijing Tiantan Hospital Affiliated to Capital Medical University developed the standard framework for the whole process of collection, preservation and transportation of whole blood samples of cerebrovascular diseases in China. The solution realizes the standard, normative, timely and reliable collection and management of whole blood samples, and can provide technical support for clinical diagnosis and treatment, disease research and drug development of cerebrovascular diseases.

Keywords

• 临床生物样本库
• 科技管理
• 脑血管病
• 全血样本
• clinical biological sample database
• scientific and technological management
• cerebrovascular disease
• whole blood sample