DIFFERENTIATED APPROACH TO THE THERAPY OF NASAL OBSTRUCTION SYNDROME

Abstract

The article presents a differentiated approach to the therapy of nasal obstruction syndrome. The authors discuss the physiological aspects of nasal breathing, the need for mucociliary clearance of the mucous layer lining the nasal epithelium, the factors of nasal resistance, and the concept of nasal cycle.The article deals with the most common causes of breathing problems such as acute infectious and allergic rhinitis and provides detailed description of the etiology, pathogenesis and role of various microorganisms in the routine evaluation of acute rhinitis. Classifications of rhinitis including allergic one are presented. The paper reviews features of seasonal and year-round disease, pathogenesis of allergic inflammation.The authors suggest that topical decongestants are used for reliable relief of nasal obstruction syndrome. In case of abundant rhinorrhoea, the combined nasal spray Otrivin Complex containing xylometazoline and ipratropium bromide is advised. If nasal secretions are combined with congestion, the authors recommend using Vibrocil containing phenylephrine and dimethindene maleate.

Keywords

• rhinitis
• nasal obstruction
• decongestants
• otrivin complex
• vibrocil