The possibility of using a topical combined antibacterial agent in the prevention of infection during surgical intervention

Abstract

The article presents the results of the clinical study on the assessment of the preventive clinical effectiveness of the topical combined antibacterial drug bacitracin/neomycin in the prevention of infection during surgical intervention.The study included 112 patients whose average age was 42.4+7.4 years. Patients were divided into groups according to the risk of infection of the surgical area (SSI) according to the criteria of D.C. Classen et al. and into subgroups according to whether standard antiseptic therapy or topical antibacterial therapy with bacitracin/neomycin was used in the postoperative period.The study demonstrated high preventive efficacy of the topical drug bacitracin/neomycin in the prevention of various clinical forms of SSI and, probably, in the prevention of seromas of postoperative wounds.

Keywords

• bacitracin
• neomycin
• local postoperative infection