The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study

Abstract

The objective of this study was to evaluate the efficacy of the noojerone in patients with moderate Alzheimer disease and to compare obtained data with results of clinical trials of memantine. This was a 24-week open - label post-marketing clinical trial conducted in Department of Geriatric Psychiatry St. Petersburg V.M. Bekhterev Psychoneurological Research Institute. Participants were 44 outpatients with moderate AD and Mini-Mental State Examination scores of 10-19 at start - point. This study have demonstrated efficacy in modifying course of AD and no significant deterioration activities of daily living and frequency and severity of behavioral symptoms, comparable with the results of memantine clinical trials.

Keywords

• деменция
• болезнь альцгеймера
• мемантин
• нооджерон
• когнитивные функции
• dementia
• alzheimer disease
• noojerone
• memantine