Consensus Statement on Proton Therapy for Prostate Cancer

Curtis M. Bryant, MD, MPH; Randal H. Henderson, MD, MBA; R. Charles Nichols, MD; William M. Mendenhall, MD; Bradford S. Hoppe, MD, MPH; Carlos E. Vargas, MD; Thomas B. Daniels, MD; C. Richard Choo, MD; Rahul R. Parikh, MD; Huan Giap, MD, PhD; Jerry D. Slater, MD; Neha Vapiwala, MD; William Barrett, MD; Akash Nanda, MD, PhD; Mark V. Mishra, MD; Seungtaek Choi, MD; Jay J. Liao, MD; Nancy P. Mendenhall, MD; the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group

doi:10.14338/IJPT-20-00031.1

International Journal of Particle Therapy (Apr 2021)

Consensus Statement on Proton Therapy for Prostate Cancer

Curtis M. Bryant, MD, MPH,
Randal H. Henderson, MD, MBA,
R. Charles Nichols, MD,
William M. Mendenhall, MD,
Bradford S. Hoppe, MD, MPH,
Carlos E. Vargas, MD,
Thomas B. Daniels, MD,
C. Richard Choo, MD,
Rahul R. Parikh, MD,
Huan Giap, MD, PhD,
Jerry D. Slater, MD,
Neha Vapiwala, MD,
William Barrett, MD,
Akash Nanda, MD, PhD,
Mark V. Mishra, MD,
Seungtaek Choi, MD,
Jay J. Liao, MD,
Nancy P. Mendenhall, MD,
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group

Affiliations

Curtis M. Bryant, MD, MPH: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
Randal H. Henderson, MD, MBA: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
R. Charles Nichols, MD: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
William M. Mendenhall, MD: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
Bradford S. Hoppe, MD, MPH: Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA
Carlos E. Vargas, MD: Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Thomas B. Daniels, MD: Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
C. Richard Choo, MD: Department of Radiation Oncology, Mayo Clinic Rochester, Rochester, MN, USA
Rahul R. Parikh, MD: Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA
Huan Giap, MD, PhD: Department of Radiation Oncology, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, USA
Jerry D. Slater, MD: Department of Radiation Oncology, Loma Linda University, Loma Linda, CA, USA
Neha Vapiwala, MD: Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
William Barrett, MD: Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA
Akash Nanda, MD, PhD: Department of Radiation Oncology, Orlando Health, Orlando, FL, USA
Mark V. Mishra, MD: Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA
Seungtaek Choi, MD: Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA
Jay J. Liao, MD: Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USA
Nancy P. Mendenhall, MD: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group

DOI: https://doi.org/10.14338/IJPT-20-00031.1
Journal volume & issue: Vol. 8, no. 2
pp. 1 – 16

Abstract

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Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.

Published in International Journal of Particle Therapy

ISSN: 2331-5180 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine; Science: Physics: Nuclear and particle physics. Atomic energy. Radioactivity
Website: https://www.sciencedirect.com/journal/international-journal-of-particle-therapy

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