Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity

• Pauline Jacquet,
• Raphaël Billot,
• Amir Shimon,
• Nathan Hoekstra,
• Céline Bergonzi,
• Anthony Jenks,
• Eric Chabrière,
• David Daudé,
• Mikael H. Elias

Affiliations

Pauline Jacquet

Gene&GreenTK, Marseille, France

Raphaël Billot

Gene&GreenTK, Marseille, France

Amir Shimon

Biotechnology Institute, University of Minnesota, St. Paul, Minnesota, United States

Nathan Hoekstra

Biotechnology Institute, University of Minnesota, St. Paul, Minnesota, United States

Céline Bergonzi

Gene&GreenTK, Marseille, France

Anthony Jenks

Department of Biochemistry, Molecular Biology and Biophysics & Biotechnology Institute, University of Minnesota, St. Paul, Minnesota, United States

Eric Chabrière

Gene&GreenTK, Marseille, France

David Daudé

Gene&GreenTK, Marseille, France

Mikael H. Elias

Biotechnology Institute, University of Minnesota, St. Paul, Minnesota, United States