Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions

Atara Nardi-Schreiber; Ayelet Gamliel; Talia Harris; Gal Sapir; Jacob Sosna; J. Moshe Gomori; Rachel Katz-Brull

doi:10.1038/s41467-017-00364-3

Nature Communications (Aug 2017)

Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions

Atara Nardi-Schreiber,
Ayelet Gamliel,
Talia Harris,
Gal Sapir,
Jacob Sosna,
J. Moshe Gomori,
Rachel Katz-Brull

Affiliations

Atara Nardi-Schreiber: Department of Radiology, Hadassah-Hebrew University Medical Center
Ayelet Gamliel: Department of Radiology, Hadassah-Hebrew University Medical Center
Talia Harris: Department of Radiology, Hadassah-Hebrew University Medical Center
Gal Sapir: Department of Radiology, Hadassah-Hebrew University Medical Center
Jacob Sosna: Department of Radiology, Hadassah-Hebrew University Medical Center
J. Moshe Gomori: Department of Radiology, Hadassah-Hebrew University Medical Center
Rachel Katz-Brull: Department of Radiology, Hadassah-Hebrew University Medical Center

DOI: https://doi.org/10.1038/s41467-017-00364-3
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 7

Abstract

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Real-time monitoring of phosphate metabolism and distribution in the live body without ionizing radiation is highly desirable. Here, the authors show dissolution-dynamic nuclear polarization technology can enable nuclear magnetic resonance detection of hyperpolarized 31P of important biological phosphates in aqueous solutions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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