Haematologica (Aug 2007)

Unrelated cord blood transplant in children with high-risk acute lymphoblastic leukemia: a long-term follow-up

  • Anna Paola Iori,
  • William Arcese,
  • Filippo Milano,
  • Elisabetta Calabrese,
  • Giovanni Fernando Torelli,
  • Walter Barberi,
  • Maria Grazia Mascolo,
  • Lidia De Felice,
  • Maria Screnci,
  • Barbarella Lucarelli,
  • Luigi Malandruccolo,
  • Maria Paola Perrone,
  • Simona Salvatori,
  • Luca Laurenti,
  • Emilia Iannella,
  • Roberto Ricci,
  • Maria Luisa Moleti,
  • Robin Foà

DOI
https://doi.org/10.3324/haematol.11271
Journal volume & issue
Vol. 92, no. 8

Abstract

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Background and Objectives The aim of this single center study was to assess the impact of pre-transplant factors on long-term follow-up in young patients affected by high-risk acute lymphoblastic leukemia (ALL) who underwent an unrelated cord blood transplant (CBT). The conditioning regimens, graft-versus-host disease (GVHD) prophylaxis and supportive policies were uniform for all patients.Design and Methods We analyzed the results of CBT performed in 30 patients, aged