Through-container quantitative analysis of hand sanitizers using spatially offset Raman spectroscopy

Nirzari Gupta; Jason D. Rodriguez; Huzeyfe Yilmaz

doi:10.1038/s42004-021-00563-6

Communications Chemistry (Sep 2021)

Through-container quantitative analysis of hand sanitizers using spatially offset Raman spectroscopy

Nirzari Gupta,
Jason D. Rodriguez,
Huzeyfe Yilmaz

Affiliations

Nirzari Gupta: Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration
Jason D. Rodriguez: Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration
Huzeyfe Yilmaz: Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration

DOI: https://doi.org/10.1038/s42004-021-00563-6
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 9

Abstract

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By combining spatially-offset Raman spectroscopy (SORS) with chemometrics, the authors demonstrate rapid, through-container analysis of commercial hand sanitizers. Both ethanol/isopropanol and contaminant alcohols are quantified regardless of container material or opacity.

Published in Communications Chemistry

ISSN: 2399-3669 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry
Website: https://www.nature.com/commschem

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