Arquivos de Gastroenterologia (Aug 2023)

THE ASSOCIATION BETWEEN COLORECTAL CANCER AND INDEX OF NUTRITIONAL QUALITY (INQ); A CASE-CONTROL STUDY

  • Maryam GHOLAMALIZADEH,
  • Soheila SHEKARI,
  • Naeemeh HASSANPOUR ARDEKANIZADEH,
  • Farhad VAHID,
  • Zahra ASLANI,
  • Mohammad Esmail AKBARI,
  • Mahdi ALEMRAJABI,
  • Ali LAVASANI,
  • Azadeh HAJIPOUR,
  • Payam HOSSEINZADEH,
  • Omid ASBAGHI,
  • Saeid DOAEI

DOI
https://doi.org/10.1590/s0004-2803.20230222-169
Journal volume & issue
Vol. 60, no. 2
pp. 217 – 223

Abstract

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ABSTRACT Background: The nutritional quality of diet may influence the risk of colorectal cancer (CRC). This study compared the Index of Nutritional Quality (INQ) of various dietary components between colorectal cancer patients and healthy controls. Methods: A total of 480 participants were enrolled in the study (160 patients with colorectal cancer as a case group and 320 healthy control). An analysis was conducted on the general characteristics of the participants, their medical histories, anthropometric indicators, physical activity, alcohol consumption, reproductive history, smoking and food intake. A valid food frequency questionnaire was used to assess nutrient intake and INQ was calculated from daily nutrient intake. Results: A Significant inverse association was found between CRC and INQ for vitamins A (OR=0.01, CI: 0.01-0.01), K (OR=0.04, CI: 0.01-0.15), and B12 (OR=0.71, CI: 0.51-0.98), B5 (OR=0.43, CI: 0.00-0.01), zinc (OR=0.35, CI: 0.13-0.95), and phosphorus (OR=0.17, 0.19-0.94). The association between the INQ of vitamin B12 and zinc with colorectal cancer was disappeared after age adjustment. There was a significant negative association between CRC with the INQ of vitamins A, K, B5, phosphorus, and calcium after further adjustments for gender, BMI, menopausal status, and total energy intake. Conclusion: CRC is significantly associated with INQ for some micronutrients. INQ can be considered as an indicator to assess clinical nutritional problems.

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