Adhesion molecules and proinflammatory cytokines in cerebrospinal fluid of multiple sclerosis patients

Abstract

In liquor 30 multiple sclerosis patients with remittent kind of clinical course the concentration of cell-cell adhesion molecules (sPECAM-1, sVCAM-1) and tumor necrosis factor (TNF) α, not interleukin-1β, was higher during the period of exacerbation compared to the period of remission. These changes are supposed to display the activity of pathogenesis important processes multiple sclerosis in cerebral tissue of multiple sclerosis patients.

Keywords

• рассеянный склероз
• молекулы межклеточной адгезии
• цитокины