Optimization and Stability Testing of Four Commercially Available Dried Blood Spot Devices for Estimating Measles and Rubella IgG Antibodies

Ojas Kaduskar; Vaishali Bhatt; Christine Prosperi; Kyla Hayford; Alvira Z. Hasan; Gururaj Rao Deshpande; Bipin Tilekar; Jeromie Wesley Vivian Thangaraj; Muthusamy Santhosh Kumar; Nivedita Gupta; Manoj V. Murhekar; William J. Moss; Sanjay M. Mehendale; Lucky Sangal; Gajanan Sapkal

doi:10.1128/mSphere.00490-21

mSphere (Aug 2021)

Optimization and Stability Testing of Four Commercially Available Dried Blood Spot Devices for Estimating Measles and Rubella IgG Antibodies

Ojas Kaduskar,
Vaishali Bhatt,
Christine Prosperi,
Kyla Hayford,
Alvira Z. Hasan,
Gururaj Rao Deshpande,
Bipin Tilekar,
Jeromie Wesley Vivian Thangaraj,
Muthusamy Santhosh Kumar,
Nivedita Gupta,
Manoj V. Murhekar,
William J. Moss,
Sanjay M. Mehendale,
Lucky Sangal,
Gajanan Sapkal

Affiliations

Ojas Kaduskar: Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
Vaishali Bhatt: Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
Christine Prosperi: Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Kyla Hayford: Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Alvira Z. Hasan: Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Gururaj Rao Deshpande: Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
Bipin Tilekar: Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
Jeromie Wesley Vivian Thangaraj: Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
Muthusamy Santhosh Kumar: Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
Nivedita Gupta: Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India
Manoj V. Murhekar: Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
William J. Moss: Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Sanjay M. Mehendale: Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India
Lucky Sangal: World Health Organization, Southeast Asia Region Office, New Delhi, India
Gajanan Sapkal: ORCiD; Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India

DOI: https://doi.org/10.1128/mSphere.00490-21
Journal volume & issue: Vol. 6, no. 4

Abstract

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Dried blood spot (DBS) collection offers various advantages over conventional methods of blood collection, especially when collecting and transporting samples for a serosurvey. Yet use of DBS requires additional processing steps in the laboratory that can add to variability in results.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal