An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance

Chun Khai Loh; Juanita Noeline Chui; Kevin Yinkit Zhuo; Ashan Canagasingham; Alexander Guminski; Warick Delprado; Thomas Eade; Matthew Winter

Urology Case Reports (Mar 2024)

An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance

Chun Khai Loh,
Juanita Noeline Chui,
Kevin Yinkit Zhuo,
Ashan Canagasingham,
Alexander Guminski,
Warick Delprado,
Thomas Eade,
Matthew Winter

Affiliations

Chun Khai Loh: Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia; North Shore Urology Research Group, Sydney, NSW, Australia; University of Sydney, Sydney, NSW, Australia; Corresponding author.Resident Medical Officer Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia
Juanita Noeline Chui: North Shore Urology Research Group, Sydney, NSW, Australia; University of Sydney, Sydney, NSW, Australia
Kevin Yinkit Zhuo: Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia; North Shore Urology Research Group, Sydney, NSW, Australia
Ashan Canagasingham: Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia; North Shore Urology Research Group, Sydney, NSW, Australia
Alexander Guminski: University of Sydney, Sydney, NSW, Australia; Department of Medical Oncology, Royal North Shore Hospital, Sydney, NSW, Australia
Warick Delprado: Douglas Hanly Moir Pathology (Sonic Healthcare), Macquarie Park, NSW, Australia
Thomas Eade: University of Sydney, Sydney, NSW, Australia; Department of Radiation Oncology, Royal North Shore Hospital, Sydney, NSW, Australia
Matthew Winter: Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia; North Shore Urology Research Group, Sydney, NSW, Australia; University of Sydney, Sydney, NSW, Australia

Journal volume & issue: Vol. 53
p. 102676

Abstract

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Microcystic adenocarcinoma is an uncommon histologic variant of prostate carcinoma. Despite its rarity, it has gained increasing recognition over the past decade for its diagnostic challenges and unclear prognostic significance.Herein, we describe a rare case of metastatic microcystic prostate adenocarcinoma, presenting with discordance between imaging and histologic findings. This report highlights the diagnostic and therapeutic challenges of this pathological entity and the importance of multidisciplinary collaboration in the management of intermediate-risk prostate cancer.

Published in Urology Case Reports

ISSN: 2214-4420 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology
Website: http://www.urologycasereports.com/

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