Nature Communications (Jun 2016)
High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
- Felix F. Loeffler,
- Tobias C. Foertsch,
- Roman Popov,
- Daniela S. Mattes,
- Martin Schlageter,
- Martyna Sedlmayr,
- Barbara Ridder,
- Florian-Xuan Dang,
- Clemens von Bojničić-Kninski,
- Laura K. Weber,
- Andrea Fischer,
- Juliane Greifenstein,
- Valentina Bykovskaya,
- Ivan Buliev,
- F. Ralf Bischoff,
- Lothar Hahn,
- Michael A. R. Meier,
- Stefan Bräse,
- Annie K. Powell,
- Teodor Silviu Balaban,
- Frank Breitling,
- Alexander Nesterov-Mueller
Affiliations
- Felix F. Loeffler
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Tobias C. Foertsch
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Roman Popov
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Daniela S. Mattes
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Martin Schlageter
- Karlsruhe Institute of Technology, Institute for Inorganic Chemistry
- Martyna Sedlmayr
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Barbara Ridder
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Florian-Xuan Dang
- Clemens von Bojničić-Kninski
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Laura K. Weber
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Andrea Fischer
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Juliane Greifenstein
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Valentina Bykovskaya
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Ivan Buliev
- Technical University of Varna
- F. Ralf Bischoff
- German Cancer Research Center
- Lothar Hahn
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Michael A. R. Meier
- Stefan Bräse
- Annie K. Powell
- Karlsruhe Institute of Technology, Institute for Inorganic Chemistry
- Teodor Silviu Balaban
- Frank Breitling
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- Alexander Nesterov-Mueller
- Karlsruhe Institute of Technology, Institute of Microstructure Technology (IMT)
- DOI
- https://doi.org/10.1038/ncomms11844
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 9
Abstract
Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor surfaces.
