Pharmaceuticals (Sep 2023)

Bibliometric Review on New Possibilities of Antimycobacterial Agents: Exploring Siderophore Desferrioxamine’s Applications as an Antimicrobial Agent

  • Patrícia Vieira de Oliveira,
  • Roseane Lustosa de Santana Lira,
  • Rafael de Abreu Lima,
  • Yasmim Costa Mendes,
  • Antenor Bezerra Martins,
  • Bruna de Oliveira de Melo,
  • Millena Ferreira Goiano,
  • Rivaldo Lira Filho,
  • Flávia Baluz Bezerra de Farias Nunes,
  • Amanda Silva dos Santos Aliança,
  • Wellyson da Cunha Araújo Firmo,
  • Rafael Cardoso Carvalho,
  • Adrielle Zagmignan,
  • Eduardo Martins de Sousa

DOI
https://doi.org/10.3390/ph16091335
Journal volume & issue
Vol. 16, no. 9
p. 1335

Abstract

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Mycobacteria cause tuberculosis and other serious diseases. Understanding their mechanisms of resistance to our immune system and exploring novel drugs are critical strategies to combat infections. A bibliometric analysis was performed to identify publication trends and critical research areas in the field of the antimicrobial activity of desferrioxamine. A total of twenty-four publications on the topic, from 2012 to 2023, were retrieved from databases including Web of Science, Scopus, PubMed, and Embase, using specific keywords. The quality of the publications was assessed using impact and productivity metrics, with an average annual publication rate of 2.1 articles. The United States emerged as the most productive country, with medicine (23.4%, 11 publications) and biochemistry, genetics, and molecular biology (21.3%, 10 publications) as the top research fields. The five most cited publications accounted for 672 citations, with a relatively low h-index (11:11). In conclusion, there has been a lack of publications on this topic in the last decade. The United States dominates production and publication in this area, and there appears to be limited exchange of knowledge, ideas, and technology within the field. Therefore, fostering international cooperation through funding is essential to facilitate further research and development of desferrioxamine-related studies.

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