Insights into Imaging (Oct 2019)
Detection of partial loss of hippocampal striation at 1.5 Tesla magnetic resonance imaging
Abstract
Abstract Objectives Partial loss of hippocampal striation (PLHS) is recently described in 3 T and 7 T MR imaging as a sensitive indicator of hippocampal sclerosis. Primary objective: We described the demographic characteristics of the population with seizure disorder having PLHS at 1.5 T MR imaging and tried to see the relation of PLHS to the classic signs of hippocampal sclerosis. Secondary objective: PLHS was also looked for in a small control population that had no seizure history. Methods This retrospective study had the approval of the institutional review board. In patients demonstrating PLHS on oblique coronal T2-weighted images, the following were recorded: age, sex, EEG findings, side of PLHS, hippocampal atrophy and high signal intensity of the hippocampus. In control population, the following were recorded: age, sex, presence/absence of PLHS and indication for imaging. Results The 116 PLHS subjects (age range 2–73 years) included 62 males and 54 females. Sixty-six (56.9%) of our PLHS subjects were less than 18 years of age: 44 (37.9%) under the age of 12 years and 22 (19%) of 12–18 years of age. Classic signs of hippocampal sclerosis were found in only 7 (6%) of the 116 subjects showing PLHS. All patients with classic signs showed PLHS on the same side. Of the control population (25 subjects, age range 3–76 years, 17 males and 8 females), one showed PLHS—he was a treated case of CNS lymphoma with gliotic changes, though there was no history of seizure. Conclusion PLHS is demonstrated at 1.5 T in both adult and paediatric population in this article and is much more common than the classic signs of hippocampal sclerosis (increased signal intensity and volume loss).
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