A new player in the game: platelet-derived extracellular vesicles in dengue hemorrhagic fever

Abstract

Thrombocytopenia and vascular leakage are clinical hallmarks in dengue hemorrhagic fever. Sung et al. present a new mechanism where platelet-derived extracellular vesicles participate in increasing vascular permeability during dengue virus infection in mice.

Keywords

• c-type lectins
• dengue
• exosomes
• microvesicles
• nets
• platelets