Nature Communications (May 2018)

Exploring patterns enriched in a dataset with contrastive principal component analysis

  • Abubakar Abid,
  • Martin J. Zhang,
  • Vivek K. Bagaria,
  • James Zou

DOI
https://doi.org/10.1038/s41467-018-04608-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 7

Abstract

Read online

Dimensionality reduction and visualization methods lack a principled way of comparing multiple datasets. Here, Abid et al. introduce contrastive PCA, which identifies low-dimensional structures enriched in one dataset compared to another and enables visualization of dataset-specific patterns.