Inequality in genetic cancer risk suggests bad genes rather than bad luck

Mats Julius Stensrud; Morten Valberg

doi:10.1038/s41467-017-01284-y

Nature Communications (Oct 2017)

Inequality in genetic cancer risk suggests bad genes rather than bad luck

Mats Julius Stensrud,
Morten Valberg

Affiliations

Mats Julius Stensrud: Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo
Morten Valberg: Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo

DOI: https://doi.org/10.1038/s41467-017-01284-y
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 8

Abstract

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Cancer heritability estimates can be obtained via decomposing trait variance into genetic and other factors. Here, the authors obtain the distribution of absolute genetic risk for 15 common cancers, and they use a number of metrics to show that the genetic risk varies considerably across individuals.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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