Journal for ImmunoTherapy of Cancer (Nov 2021)
520 Preliminary biomarker and pharmacodynamic (PD) activity of the TGFβ inhibitor SAR439459, alone or in combination with cemiplimab, in a phase 1 clinical study in patients with advanced solid tumors
- Rui Wang,
- Ivan Borbath,
- Patrícia Martin,
- Armando Santoro,
- Bernard Doger,
- Elena Garralda,
- Oliver Bechter,
- Giovanni Abbadessa,
- Debbie Robbrecht,
- Grob Jean-Jacques,
- Butler Marcus,
- Cheng Tina,
- Bennouna Jaafar,
- Massimo Di Nicola,
- Alejo Rodriguez -Vida,
- Dirk Schadendof,
- Brigitte Demers,
- Amele Amrate,
- Tun Tun Lin,
- Manisha Brahmachary,
- Joon Sange Lee,
- Joachim Theilhaber,
- Rob Pomponio
Affiliations
- Rui Wang
- Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China
- Ivan Borbath
- 2 Université catholique de Louvain, IREC, Brussels, Belgium
- Patrícia Martin
- 2Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University
- Armando Santoro
- Medical Oncology and Hematology Unit, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy
- Bernard Doger
- 5Fundacion Jimenez Díaz, Madrid, Spain
- Elena Garralda
- 6Vall d’Hebron Institute of Oncology, Barcelona, Spain
- Oliver Bechter
- 1University Hospitals Leuven, Leuven, Belgium
- Giovanni Abbadessa
- 1Sanofi, Cambridge, USA
- Debbie Robbrecht
- 1Erasmus Medical Centre, Rotterdam, Netherlands
- Grob Jean-Jacques
- 2APHM – Hopital de la Timone, Marseille, France
- Butler Marcus
- 7Princess Margaret Hospital, NA, Canada
- Cheng Tina
- 8Tom Baker Cancer Centre, NA, Canada
- Bennouna Jaafar
- 10CHU de Nantes – Hotel Dieu, NA, France
- Massimo Di Nicola
- 11Istituto Nazionale dei Tumori, NA, Italy
- Alejo Rodriguez -Vida
- 14Hospital Del Mar, NA, Spain
- Dirk Schadendof
- 15Universitatsklinikum Essen, NA, Germany
- Brigitte Demers
- 17Sanofi, Cambridge, MA, USA
- Amele Amrate
- 17Sanofi, Cambridge, MA, USA
- Tun Tun Lin
- 17Sanofi, Cambridge, MA, USA
- Manisha Brahmachary
- 17Sanofi, Cambridge, MA, USA
- Joon Sange Lee
- 17Sanofi, Cambridge, MA, USA
- Joachim Theilhaber
- 17Sanofi, Cambridge, MA, USA
- Rob Pomponio
- 17Sanofi, Cambridge, MA, USA
- DOI
- https://doi.org/10.1136/jitc-2021-SITC2021.520
- Journal volume & issue
-
Vol. 9,
no. Suppl 2
Abstract
No abstracts available.