Bionomik Schistosoma japonicum pada Mencit (Mus musculus) di Laboratorium

Abstract

Schistosomiasis is still a public health problem in endemic areas. Schistosomiasis in Indonesia was distributed in Napu, Lindu, and Bada Highlands. Schistosomiasis control was complex because so many aspect were related with schistosoma life cycle. The aim of this experiment was to support the study about schistosoma life cycle and also to provide antigen collection to develop a sero diagnostic kit for schistosomiasis. This experiment was conducted in laboratory using Mus musculus. The animal were infected with serkaria of S. ja[onicum for 3 months and their feces were examined by microscop to detect S. japonicum eggs. All of the experimental animal which infected were positive S. japonicum. 27 pairs of S. japonicum were found in hepatic tissues of the infected animal and formed granuloma in hepatic tissues. Schistosoma japonicum can developed in Mus musculus although it's size became smaller.

Keywords

• serkaria, Schistosoma japonicum, Mus musculus