Hyperhomocysteinemia and its correction in posttrombotic syndrome of the lower limbs

Abstract

The article is about hyperhomocysteinemia which retards recanalization processes after deep vein thrombosis and leads to the lower extremities post-thrombotic syndrome. Levels of blood homocysteine were determined at admission, after 1 and 3 months after the acute thrombosis of the deep veins of the lower extremities. Increased levels of homocysteine were revealed. Maximum concentration of homocysteine was 31.6 mmol/l, which corresponds to moderate hyperhomocysteinemia. In patients receiving anticoagulants for 3 months the level of homocysteine slightly decreased. Prescription of vitamins B6, B9, B12 allows significantly decrease the homocysteine levels, improve health outcomes, reduce the number of patients with class C3-4.

Keywords

• посттромботический синдром
• гомоцистеин
• фолиевая кислота
• витамины В
• В
• посттромботический синдром
• гомоцистеин
• фолиевая кислота
• витамины В
• В