Green Synthesis of Cerium Oxide Nanoparticles (CeO2 NPs) and Their Antimicrobial Applications: A Review

Abstract

Muhammad Nadeem,1 Ramsha Khan,1 Komal Afridi,1 Akhtar Nadhman,1 Sana Ullah,2 Sulaiman Faisal,1 Zia Ul Mabood,1 Christophe Hano,3 Bilal Haider Abbasi2 1Institute of Integrative Biosciences, CECOS University of IT and Emerging Sciences, Peshawar 25100, KPK, Pakistan; 2Department of Biotechnology, Quaid I Azam University, Islamabad 45320, Pakistan; 3Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Plant Lignans Team, INRAE USC1328, Université d’Orléans, Eure Et Loir Campus, Chartres F28000, FranceCorrespondence: Muhammad Nadeem Email [email protected]: During the last decade green synthesized cerium oxide nanoparticles (CeO2 NPs) attracted remarkable interest in various fields of science and technology. This review, explores the vast array of biological resources such as plants, microbes, and other biological products being used in synthesis of CeO2 NPs. It also discusses their biosynthetic mechanism, current understandings, and trends in the green synthesis of CeO2 NPs. Novel therapies based on green synthesized CeO2 NPs are illustrated, in particular their antimicrobial potential along with attempts of their mechanistic elucidation. Overall, the main objective of this review is to provide a rational insight of the major accomplishments of CeO2 NPs as novel therapeutics agents for a wide range of microbial pathogens and combating other diseases.Keywords: nanotechnology, green synthesis, cerium oxide, nanoparticles, antimicrobial, infections, biomedical

Keywords

• nanotechnology
• green synthesis
• cerium oxide
• nanoparticles
• antimicrobial
• infections
• biomedical