Clinical cytohistopathological study of benign thyroid disease in Sidi Bel Abbes region, Western Algeria

Abstract

Background and objective Benign thyroid disease is the most common disorder of the endocrine system. Our study aimed to analyze the clinical and cytohistological diagnosis of benign thyroid disease in western Algeria (Sidi Bel Abbes region) as well as define the characteristics of this pathology. Patients and methods This was an epidemiological retrospective descriptive study of patients with benign thyroid disease, performed at the Department of Surgery, University Hospital Dr Hassani Abdelkader, in Sidi Bel Abbes, during the period of 10 years (from January 2004 to December 2013).The medical data were analyzed using the statistical package for the social sciences (SPSS, version 20.0). Results A total of 430 patients were recorded (33 men and 397 women). The average age of patients at diagnosis was 45.02 ± 13.41 years. Our survey demonstrated that 42.09% of the population had solitary nodular goiters, 27.44% had multinodular goiter, 21.63% of patients had binodular goiter, 5.35% had solitary nodule, and finally 3.49% were affected by goiter diseases. Fine-needle aspiration cytology analysis revealed that benign dystrophic lesion was present in most cases (25.93%), followed by hyperplasia (22.56%) and suspicion of malignancy (14.14%). Our results revealed that benign thyroid disease could be recurrent and hereditary. Histopathologically, colloid goiter, multinodular goiter, and vesicular adenoma were recorded in 23.75, 21.07, and 13.03%, respectively. Conclusion According to our results, benign thyroid disease in the region of Sidi Bel Abbes is a frequent health illness that is predominant in young women compared with young men of same age.

Keywords

• clinical
• cytohistological
• diagnosis
• surgery
• thyroid