Epidural glucocorticoid use for vertebrogenic pain

Abstract

The literature review deals with the use of glucocorticoids (GC) for nonspecific vertebrogenic pain and radiculopathy. The pathophysiology of radiculopathy and the role of mechanical and chemical components in the development of pain syndrome are discussed. The data of clinical trials analyzing the efficiency of epidural GC use, as well as possible indications for this therapy and its adverse reactions are under consideration. The available concepts of the analgesic effect of epidural CG are discussed.

Keywords

• glucocorticoids
• epidural injection
• back pain
• lumbar ischialgia
• radiculopathy